Thus, at the early stages of process design, one sets course for the future process. Furthermore, each decision reduces the scope of the impact of future decisions. Especially at an early stage of process design, each decision limits the range of future choices. With each decision made, the designed process slowly assumes shape. Initially, as the engineer begins to sketch the flowsheet, there are an incredibly large number of process alternatives. Each decision reduces the degrees of freedom of the process design. During the stage of conceptual process design, most design decisions are yet to be made, as the design will become more detailed with each decision. Process engineers are expected to design safe, dependable and cost-efficient processes. Keywords: Chemical process design Process modeling Simulation and optimization Uncertainty Process performance measures Convergence Process Simulators. It is shown how this methodology yields more details about limitations of a studied process design. To facilitate automation, a novel relaxation-based heuristic to differentiate between numerical and physical infeasibility when simulations do not converge is introduced. In this work, an approach to quantify the effect of uncertainty on a process design in order to enhance comparisons among different designs is presented. The complexity of typical process models limits intuitive engineering estimates to judge the impact of uncertain parameters on the proposed design. Still, process engineers are expected to design safe, dependable and cost-efficient processes under these conditions. E-mail: major challenge in chemical process design is to make design decisions based on partly incomplete or imperfect design input data. E-mail: IICurrently: Massachusetts Institute of Technology, Department of Chemical Engineering, 66-363, 77 Massachusetts Ave, Cambridge, MA 02139, USA. This is an extended version of the manuscript presented at the PSE 2009 -10th International Symposium on Process Systems Engineering, 2009, Salvador, Brazil, and published in Computer Aided Chemical Engineering, vol. To whom correspondence should be addressed Supporting chemical process design under uncertaintyĪ.
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